What is arthralgia, one of the side effects of covid vaccines

What is arthralgia, one of the side effects of covid vaccines

Among the various side effects that the mRNA vaccines Pfizer and Moderna have brought, arthralgia is one of the least heard of, although the relationship between the two factors was already warned at the end of summer 2021. Curiously , because It is one of the most common, although the truth is that these are short episodes and the vast majority are not serious.according to the Spanish Agency for Medicines and Health Products (AEMPS).

Arthralgia: meaning, what is it and how it affects the body

The meaning of arthralgia is joint pain, and can be caused by a large number of factors, from trauma to infectious diseases such as measles, influenza or hepatitis. Cases of arthralgia have also been observed in patients with degenerative diseases such as osteoarthritis or osteoarthritis; it also appears in ppeople with immune system disorders and morbidly obese, tendonitis or bursitis; Bursitis is pain that affects the small, fluid-filled sacs (bursae) that cushion the contact between bones, tendons, and muscles around joints.

Arthralgia too It can appear due to a specific overwork or due to a history of rheumatoid arthritis, as well as radiculopathies (pinched nerves) osteomyelitis (bone infection derived from blood or adjacent tissues) and vasculopathies or blood vessel disorders. The pain starts in the joint area and usually leads to inflammation of the affected area, stiffness and redness of the skin. When it comes to infectious cases, the onset of fever and chills is not uncommon.

Obviously, arthralgia can also appear due to factors outside the pathologies described, especially in the elderly, who suffer more from sudden changes in temperature. The onset of cold weather, although tempered these first days of winter by milder temperatures, is another factor that can exacerbate joint pain in people who have affected, for example, the aforementioned synovial tissue.

Arthralgia in covid vaccines

The latest pharmacovigilance report on covid-19 vaccines, published on December 1, updated the data concerning this consequence of vaccines in a certain group of vaccinated people. This report specified that among the most frequently reported events were fever and malaise (the most frequent since the start of the pandemic), nervous system disorders (headache and dizziness) and the musculoskeletal system (myalgia and arthralgia).

If we refer to the figures in the report, they surprise by their very low incidence. As of November 13, 2022, 5,405,069 doses of bivalent Comirnaty (Pfizer Original/Omicron BA.4-5) have been administered in Spain and there are only 117 adverse event reports. With this vaccine, cases of arthralgia have been reported in 4% of cases.

The reported with the original Spikevax (Moderna) vaccine were 5% of all adverse events after administration (a total of 19,742 were the side effects recorded after the administration of 24,128,984 doses). However, the bivalent vaccine Spikevax (Original/Omicron BA.1), which was administered much less in Spain, recorded a higher percentage of cases of arthralgia; increase to 20% of all adverse events45 reports after 172,594 doses of bivalent Moderna.

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